Hsp72 and Hsp90α mRNA transcription is characterised by large, sustained changes in core temperature during heat acclimation.

ABSTRACT: Increased intracellular heat shock protein-72 (Hsp72) and heat shock protein-90α (Hsp90α) have been implicated as important components of acquired thermotolerance, providing cytoprotection during stress. This experiment determined the physiological responses characterising increases in Hsp72 and Hsp90α mRNA on the first and tenth day of 90-min heat acclimation (in 40.2 °C, 41.0 % relative humidity (RH)) or equivalent normothermic training (in 20 °C, 29 % RH). Pearson's product-moment correlation and stepwise multiple regression were performed to determine relationships between physiological [e.g. (T_rec, sweat rate (SR) and heart rate (HR)] and training variables (exercise duration, exercise intensity, work done), and the leukocyte Hsp72 and Hsp90α mRNA responses via reverse tran

SUBMITTER: Gibson OR 

PROVIDER: S-EPMC5083671 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature