Ontology highlight
ABSTRACT:
SUBMITTER: Jiang Z
PROVIDER: S-EPMC5083973 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Jiang Zhengdong Z Chen Xin X Chen Ke K Sun Liankang L Gao Luping L Zhou Cancan C Lei Meng M Duan Wanxing W Wang Zheng Z Ma Qingyong Q Ma Jiguang J
Nutrients 20160923 10
Resveratrol, a natural polyphenol present in most plants, inhibits the growth of numerous cancers both in vitro and in vivo. Aberrant expression of YAP has been reported to activate multiple growth-regulatory pathways and confer anti-apoptotic abilities to many cancer cells. However, the role of resveratrol in YES-activated protein (YAP) expression and that of YAP in pancreatic cancer cells' response to gemcitabine resistance remain elusive. In this study, we found that resveratrol suppressed th ...[more]