Genetic variation in Tunisia in the context of human diversity worldwide.

ABSTRACT:

Objectives

North Africa has a complex demographic history of migrations from within Africa, Europe, and the Middle East. However, population genetic studies, especially for autosomal genetic markers, are few relative to other world regions. We examined autosomal markers for eight Tunisian and Libyan populations in order to place them in a global context.

Materials and methods

Data were collected by TaqMan on 399 autosomal single nucleotide polymorphisms on 331 individuals from Tunisia and Libya. These data were combined with data on the same SNPs previously typed on 2585 individuals from 57 populations from around the world. Where meaningful, close by SNPs were combined into multiallelic haplotypes. Data were evaluated by clustering, principal components, and population tree

SUBMITTER: Cherni L 

PROVIDER: S-EPMC5084816 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature