Increased number of negative lymph nodes is associated with improved survival outcome in node positive gastric cancer following radical gastrectomy.

ABSTRACT: The concept of negative lymph node (NLN) counts has recently attracted attention as a prognostic indicator in various cancer. However, the correlation between NLN counts and patient prognosis in the setting of gastric cancer is not fully studied. Surveillance, Epidemiology, and End Results Program (SEER)-registered gastric cancer patients were used for analysis in this study. Clinicopathological characteristics, including race, age, gender, and tumor stage, grade, and cause specific survival were collected. Univariate and multivariate Cox proportional hazards model were used to assess the risk factors for survival. As results, X-tile plots identified 3 and 9 as the optimal cutoff value to divide the patients into high, middle and low risk subsets in terms of cause specific survival, and NL

SUBMITTER: Shi RL 

PROVIDER: S-EPMC5085211 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature