The diagnostic value of ⁹⁹Tc^M-2-(2-methyl-5-nitro-1H-imidazol-1-yl) ethyl dihydrogen phosphate hypoxia imaging and its evaluation performance for radiotherapy efficacy in non-small-cell lung cancer.

ABSTRACT:

Background and aim

This study was designated to assess the diagnostic value of ⁹⁹Tc^M-2-(2-methyl-5-nitro-1H-imidazol-1-yl) ethyl dihydrogen phosphate (⁹⁹Tc^M-MNLS) hypoxia imaging and its evaluation performance for radiotherapy efficacy in patients with non-small-cell lung cancer (NSCLC).

Patients and methods

A total of 61 patients with NSCLC were selected for this study. All patients were injected with ⁹⁹Tc^M-MNLS within 1 week prior to radiotherapy and they were injected with ⁹⁹Tc^M-MNLS again 3 months after radiotherapy. Qualitative analysis along with semiquantitative analysis results were obtained from hypoxia imaging. Meanwhile, the effect of radiotherapy on patients with NSCLC

SUBMITTER: Yang Y 

PROVIDER: S-EPMC5085314 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature