Universal Stress Proteins as New Targets for Environmental and Therapeutic Interventions of Schistosomiasis.

ABSTRACT: In spite of various control measures and eradication methods that have been in progress, schistosomiasis still prevails as one of the most prevalent debilitating parasitic diseases, typically affecting the poor and the underprivileged that are predominantly concentrated in sub-Saharan Africa. The parasitic schistosome blood fluke responsible for causing the disease completes its complex developmental cycle in two hosts: humans and freshwater snails, where they physically undergo gross modifications to endure the different conditions associated with each host. Just like any other organism, the worm possesses mechanisms that help them respond to environmental insults. It has been hypothesized that a special class of proteins known as Universal Stress Proteins (USPs) are up-regulated during s

SUBMITTER: Masamba P 

PROVIDER: S-EPMC5086711 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature