In vivo delineation of subdivisions of the human amygdaloid complex in a high-resolution group template.

ABSTRACT: The nuclei of the human amygdala remain difficult to distinguish in individual subject structural magnetic resonance images. However, interpretation of the amygdala's role in whole brain networks requires accurate localization of functional activity to a particular nucleus or subgroup of nuclei. To address this, high spatial resolution, three-dimensional templates, using joint high accuracy diffeomorphic registration of T1- and T2-weighted structural images from 168 typical adults between 22 and 35 years old released by the Human Connectome Project were constructed. Several internuclear boundaries are clearly visible in these templates, which would otherwise be impossible to delineate in individual subject data. A probabilistic atlas of major nuclei and nuclear groups was constructed in th

SUBMITTER: Tyszka JM 

PROVIDER: S-EPMC5087325 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature