Sodium Excretion and the Risk of Cardiovascular Disease in Patients With Chronic Kidney Disease.

ABSTRACT:

Importance

Patients with chronic kidney disease (CKD) are at an increased risk of cardiovascular disease (CVD) compared with the general population. Prior studies have produced contradictory results on the association of dietary sodium intake with risk of CVD, and this relationship has not been investigated in patients with CKD.

Objective

To evaluate the association between urinary sodium excretion and clinical CVD events among patients with CKD.

Design, setting, and participants

A prospective cohort study of patients with CKD from 7 locations in the United States enrolled in the Chronic Renal Insufficiency Cohort Study and followed up from May 2003 to March 2013.

Exposures

The cumulative mean of urinary sodium excretion from three 24-hour urinary measurements

SUBMITTER: Mills KT 

PROVIDER: S-EPMC5087595 | biostudies-literature | 2016 May 24-31

REPOSITORIES: biostudies-literature