Ontology highlight
ABSTRACT:
SUBMITTER: Pearson JC
PROVIDER: S-EPMC5087646 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Pearson Joseph C JC McKay Daniel J DJ Lieb Jason D JD Crews Stephen T ST
Development (Cambridge, England) 20161001 20
One of the key issues in studying transcriptional regulation during development is how to employ genome-wide assays that reveals sites of open chromatin and transcription factor binding to efficiently identify biologically relevant genes and enhancers. Analysis of Drosophila CNS midline cell development provides a useful system for studying transcriptional regulation at the genomic level due to a large, well-characterized set of midline-expressed genes and in vivo validated enhancers. In this st ...[more]