Effect of Age on Breast Cancer Patient Prognoses: A Population-Based Study Using the SEER 18 Database.

ABSTRACT:

Background

Age is an important risk factor for breast cancer, but data regarding whether patient age at diagnosis is related to breast cancer survival are conflicting. This population-based study evaluated the effect of age on breast cancer prognosis and identified outcome-related factors.

Patients and methods

We searched the Surveillance, Epidemiology, and End Results (SEER) database and enrolled female primary non-metastatic cases. Patients were subdivided into seven groups, and analyses of the associations between age and overall survival (OS) and breast cancer-specific survival (BCSS) were carried out using the Kaplan-Meier method and Cox regression model, respectively. We also assessed differences in survival among three specific age groups, using the ages of 30 and 50

SUBMITTER: Chen HL 

PROVIDER: S-EPMC5087840 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature