Robustness of Automated Methods for Brain Volume Measurements across Different MRI Field Strengths.

ABSTRACT:

Introduction

Pooling of multicenter brain imaging data is a trend in studies on ageing related brain diseases. This poses challenges to MR-based brain segmentation. The performance across different field strengths of three widely used automated methods for brain volume measurements was assessed in the present study.

Methods

Ten subjects (mean age: 64 years) were scanned on 1.5T and 3T MRI on the same day. We determined robustness across field strength (i.e., whether measured volumes between 3T and 1.5T scans in the same subjects were similar) for SPM12, Freesurfer 5.3.0 and FSL 5.0.7. As a frame of reference, 3T MRI scans from 20 additional subjects (mean age: 71 years) were segmented manually to determine accuracy of the methods (i.e., whether measured volumes corresponded

SUBMITTER: Heinen R 

PROVIDER: S-EPMC5087903 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature