Randomized controlled trial of remote ischemic preconditioning and atrial fibrillation in patients undergoing cardiac surgery.

ABSTRACT:

Aim

To study whether remote ischemic preconditioning (RIPC) has an impact on clinical outcomes, such as post-operative atrial fibrillation (POAF).

Methods

This was a prospective, single-center, single-blinded, randomized controlled study. One hundred and two patients were randomized to receive RIPC (3 cycles of 5 min ischemia and 5 min reperfusion in the upper arm after induction of anesthesia) or no RIPC (control). Primary outcome was POAF lasting for five minutes or longer during the first seven days after surgery. Secondary outcomes included length of hospital stay, incidence of inpatient mortality, myocardial infarction, and stroke.

Results

POAF occurred at a rate of 54% in the RIPC group and 41.2% in the control group (P = 0.23). No statistically significa

SUBMITTER: Lotfi AS 

PROVIDER: S-EPMC5088368 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature