Directional deep brain stimulation of the subthalamic nucleus: A pilot study using a novel neurostimulation device.

ABSTRACT:

Introduction

A novel neurostimulation system allows steering current in horizontal directions by combining segmented leads and multiple independent current control. The aim of this study was to evaluate directional DBS effects on parkinsonian motor features and adverse effects of subthalamic neurostimulation.

Methods

Seven PD patients implanted with the novel directional DBS system for bilateral subthalamic DBS underwent an extended monopolar review session during the first postoperative week, in which current thresholds were determined for rigidity control and stimulation-induced adverse effects using either directional or ring-mode settings.

Results

Effect or adverse effect thresholds were modified by directional settings for each of the 14 STN leads. Magnitude of c

SUBMITTER: Steigerwald F 

PROVIDER: S-EPMC5089579 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature