Systematic Review of the Diagnostic Accuracy of Haptoglobin, Serum Amyloid A, and Fibrinogen versus Clinical Reference Standards for the Diagnosis of Bovine Respiratory Disease.

ABSTRACT:

Background

Bovine respiratory disease (BRD) is a worldwide animal health concern especially in feedlot, dairy, and veal calves. One of the greatest challenges is the absence of a gold standard for achieving an accurate antemortem diagnosis. Various blood markers, including the acute-phase proteins (AAP), have been proposed as potential valuable tools for BRD diagnosis.

Objectives

To perform a systematic review of the literature to assess the accuracy of selected APP (haptoglobin [Hp], serum amyloid A [SAA], and fibrinogen [Fb]) as diagnostic tools for cattle with naturally occurring BRD when compared with clinical reference standards of diagnosis.

Methods

This review was performed with eligible studies selected from CAB Abstract and MEDLINE from 1946 to 2015, as well

SUBMITTER: Abdallah A 

PROVIDER: S-EPMC5089617 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature