Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa.

ABSTRACT: Anorexia nervosa (AN) is a severe mental illness characterized by problems with self-perception. Whole-brain neural activations in healthy women, women with AN and women in long-term weight recovery following AN were compared using two functional magnetic resonance imaging tasks probing different aspects of self-perception. The Social Identity-V2 task involved consideration about oneself and others using socially descriptive adjectives. Both the ill and weight-recovered women with AN engaged medial prefrontal cortex less than healthy women for self-relevant cognitions, a potential biological trait difference. Weight-recovered women also activated the inferior frontal gyri and dorsal anterior cingulate more for direct self-evaluations than for reflected self-evaluations, unlike both other g

SUBMITTER: McAdams CJ 

PROVIDER: S-EPMC5091684 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature