Interdependency of brassinosteroid and auxin signaling in Arabidopsis.

ABSTRACT: How growth regulators provoke context-specific signals is a fundamental question in developmental biology. In plants, both auxin and brassinosteroids (BRs) promote cell expansion, and it was thought that they activated this process through independent mechanisms. In this work, we describe a shared auxin:BR pathway required for seedling growth. Genetic, physiological, and genomic analyses demonstrate that response from one pathway requires the function of the other, and that this interdependence does not act at the level of hormone biosynthetic control. Increased auxin levels saturate the BR-stimulated growth response and greatly reduce BR effects on gene expression. Integration of these two pathways is downstream from BES1 and Aux/IAA proteins, the last known regulatory factors acting down

SUBMITTER: Nemhauser JL 

PROVIDER: S-EPMC509407 | biostudies-literature | 2004 Sep

REPOSITORIES: biostudies-literature