Insights into the innate immunome of actiniarians using a comparative genomic approach.

ABSTRACT:

Background

Innate immune genes tend to be highly conserved in metazoans, even in early divergent lineages such as Cnidaria (jellyfish, corals, hydroids and sea anemones) and Porifera (sponges). However, constant and diverse selection pressures on the immune system have driven the expansion and diversification of different immune gene families in a lineage-specific manner. To investigate how the innate immune system has evolved in a subset of sea anemone species (Order: Actiniaria), we performed a comprehensive and comparative study using 10 newly sequenced transcriptomes, as well as three publically available transcriptomes, to identify the origins, expansions and contractions of candidate and novel immune gene families.

Results

We characterised five conserved genes and gene

SUBMITTER: van der Burg CA 

PROVIDER: S-EPMC5094078 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature