Vertical Transmission of Zika Virus in Aedes aegypti Mosquitoes.

ABSTRACT: Previous experimental studies have demonstrated that a number of mosquito-borne flavivirus pathogens are vertically transmitted in their insect vectors, providing a mechanism for these arboviruses to persist during adverse climatic conditions or in the absence of a susceptible vertebrate host. In this study, designed to test whether Zika virus (ZIKV) could be vertically transmitted, female Aedes aegypti and Aedes albopictus were injected with ZIKV, and their F₁ adult progeny were tested for ZIKV infection. Six of 69 Ae. aegypti pools, comprised of a total of 1,738 F₁ adults, yielded ZIKV upon culture, giving a minimum filial infection rate of 1:290. In contrast, none of 803 F₁ Ae. albopictus adults (32 pools) yielded ZIKV. The MFIR for Ae. aegypti was compa

SUBMITTER: Thangamani S 

PROVIDER: S-EPMC5094235 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature