Age influence on renalase and catecholamines concentration in hypertensive patients, including maintained dialysis.

ABSTRACT:

Background

Hypertension in elderly patients is one of the main problems in cardiovascular diseases. The sympathetic nervous system hyperactivity seen in older patients is a known risk factor for hypertension and other cardiovascular events as well as chronic kidney disease. Renalase, secreted by the kidney and circulated in blood, may regulate the sympathetic tone by catecholamine degradation and in this way has an impact on cardiovascular and renal complications.

Objective

To assess the impact of age on renalase and catecholamine concentration in hypertensive patients, including those on dialyses and its possible relation to blood pressure control and cardiovascular disease.

Methods

The study cohort of 211 patients was divided into two groups according to age below 6

SUBMITTER: Zbroch E 

PROVIDER: S-EPMC5094527 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature