Cytomegalovirus infection in immunocompetent critically ill adults: literature review.

ABSTRACT: Cytomegalovirus (CMV) infection is increasingly recognized in critically ill immunocompetent patients. Some studies have demonstrated an association between CMV disease and increased mortality rates, prolonged intensive care unit and hospital length of stay, prolonged mechanical ventilation, and nosocomial infections. However, there is a considerable controversy whether such association represents a causal relationship between CMV disease and unfavorable outcomes or just a marker of the severity of the critical illness. Detection of CMV using polymerase chain reaction and CMV antigenemia is the standard diagnostic approach. CMV may have variety of clinical manifestations reflecting the involvement of different organ systems. Treatment of CMV in critical care is challenging due to diagnosti

SUBMITTER: Al-Omari A 

PROVIDER: S-EPMC5095093 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature