Accelerated Accumulation of Multimorbidity After Bilateral Oophorectomy: A Population-Based Cohort Study.

ABSTRACT:

Objective

To study the association between bilateral oophorectomy and the rate of accumulation of multimorbidity.

Patients and methods

In this historical cohort study, the Rochester Epidemiology Project records-linkage system was used to identify all premenopausal women who underwent bilateral oophorectomy before age 50 years between January 1, 1988, and December 31, 2007, in Olmsted County, Minnesota. Each woman was randomly matched to a referent woman born in the same year (±1 year) who had not undergone bilateral oophorectomy. We studied the rate of accumulation of 18 common chronic conditions over a median of approximately 14 years of follow-up.

Results

Although women who underwent bilateral oophorectomy already had a higher multimorbidity burden at the time of oo

SUBMITTER: Rocca WA 

PROVIDER: S-EPMC5097693 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature