Ontology highlight
ABSTRACT:
SUBMITTER: Dessing MC
PROVIDER: S-EPMC5098240 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Scientific reports 20161107
NLRP3 (NOD-like receptor family, pyrin domain containing 3) is a member of the inflammasome family and is of special interest in renal disease. Experimental studies have shown that Nlrp3 plays a significant role in the induction of renal damage and dysfunction in acute and chronic renal injury. However, the role of NLRP3 in human renal disease is completely unknown. From a retrospective cohort study, we determined in 1271 matching donor and recipient samples if several NLRP3 single nucelotide po ...[more]