Maternal Alcohol Use During Pregnancy and Associated Morbidities in Very Low Birth Weight Newborns.

ABSTRACT:

Background

We hypothesized that maternal alcohol use occurs in pregnancies that end prematurely and that in utero alcohol exposure is associated with an increased risk of morbidities of premature newborns.

Methods

In an observational study of mothers who delivered very low birth weight newborns (VLBW) ≤1,500 g, maternal alcohol use was determined via a standardized administered questionnaire. We compared the effect of maternal drinking on the odds of developing late-onset sepsis (LOS), bronchopulmonary dysplasia (BPD), death, BPD or death, days on oxygen or any morbidity (either LOS, BPD or death). The effect of drinking amounts (light versus heavy) was also evaluated.

Results

A total of 129 subjects who delivered 143 VLBW newborns were enrolled. Approximately 1 in 3

SUBMITTER: Gauthier TW 

PROVIDER: S-EPMC5098418 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature