Reward-Based Spatial Learning in Teens With Bulimia Nervosa.

ABSTRACT:

Objective

To assess the functioning of mesolimbic and fronto-striatal areas involved in reward-based spatial learning in teenaged girls with bulimia nervosa (BN) that might be involved in the development and maintenance of maladaptive behaviors characteristic of the disorder.

Method

We compared functional magnetic resonance imaging blood oxygen level-dependent response in 27 adolescent girls with BN to that of 27 healthy, age-matched control participants during a reward-based learning task that required learning to use extra-maze cues to navigate a virtual 8-arm radial maze to find hidden rewards. We compared groups in their patterns of brain activation associated with reward-based spatial learning versus a control condition in which rewards were unexpected because they were

SUBMITTER: Cyr M 

PROVIDER: S-EPMC5098471 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature