Cingulo-opercular network efficiency mediates the association between psychotic-like experiences and cognitive ability in the general population.

ABSTRACT:

Background

Psychosis is hypothesized to occur on a spectrum between psychotic disorders and healthy individuals. In the middle of the spectrum are individuals who endorse psychotic-like experiences (PLEs) that may not impact daily functioning or cause distress. Individuals with PLEs show alterations in both cognitive ability and functional connectivity of several brain networks, but the relationship between PLEs, cognition, and functional networks remains poorly understood.

Methods

We analyzed resting-state fMRI data, a range of neuropsychological tasks, and questions from the Achenbach Adult Self Report (ASR) in 468 individuals from the Human Connectome Project. We aimed to determine whether global efficiency of specific functional brain networks supporting higher-order cog

SUBMITTER: Sheffield JM 

PROVIDER: S-EPMC5098904 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature