Long-Term Results of Early Surgery versus Conventional Treatment for Infective Endocarditis Trial.

ABSTRACT:

Background and objectives

Compared with conventional treatment, early surgery significantly reduced the composite end point of all-cause death and embolic events during hospitalization, but long-term data in this area are lacking. This study sought to compare long-term outcomes of early surgery with a conventional treatment strategy in patients with infective endocarditis (IE) and large vegetations.

Subjects and methods

The Early Surgery versus Conventional Treatment in Infective Endocarditis (EASE) trial randomly assigned patients with left-sided IE, severe valve disease and large vegetation to early surgery (37 patients) or conventional treatment groups (39 patients). The pre-specified end points were all-cause death, embolic events, recurrence of IE and repeat hospitaliza

SUBMITTER: Kang DH 

PROVIDER: S-EPMC5099342 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature