A systematic review of tranexamic acid in hip fracture surgery.

ABSTRACT:

Aim

To systematically examine and quantify the efficacy and safety of tranexamic acid in hip fracture surgery.

Methods

A systematic literature search was conducted using Medline, EMBASE, AMED, CiNAHL, and the Cochrane Central Registry of Controlled Trials. Two assessors independently screened search outputs for potentially relevant articles which met the eligibility criteria. The primary outcome measure was requirement of post-operative blood transfusion. Risk of bias assessment was performed using the Cochrane Collaboration's risk of bias tool for randomized controlled trials (RCTs) and the ROBINS-I tool for observational studies. Meta-analysis was performed to estimate risk ratio (RR), risk difference (RD) and mean difference (MD) values for dichotomous and continuous data

SUBMITTER: Farrow LS 

PROVIDER: S-EPMC5099561 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature