Human fallopian tube epithelium co-culture with murine ovarian follicles reveals crosstalk in the reproductive cycle.
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ABSTRACT:
SUBMITTER: Zhu J
PROVIDER: S-EPMC5099996 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
Human fallopian tube epithelium co-culture with murine ovarian follicles reveals crosstalk in the reproductive cycle.
Zhu Jie J Xu Yuanming Y Rashedi Alexandra S AS Pavone Mary Ellen ME Kim J Julie JJ Woodruff Teresa K TK Burdette Joanna E JE
Molecular human reproduction 20160819 11
<h4>Study question</h4>Do interactions between human fallopian tube epithelium and murine follicles occur during an artificial reproductive cycle in a co-culture system in vitro?<h4>Summary answer</h4>In a co-culture system, human fallopian tissues responded to the menstrual cycle mimetic by changes in morphology and levels of secreted factors, and increasing murine corpus luteum progesterone secretion.<h4>What is known already</h4>The entire fallopian tube epithelium, including ciliated and sec ...[more]
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