Physiological effects of invasive ventilation with neurally adjusted ventilatory assist (NAVA) in a crossover study.

ABSTRACT:

Background

Neurally Adjusted Ventilatory Assist (NAVA) is a mode of assisted mechanical ventilation that delivers inspiratory pressure proportionally to the electrical activity of the diaphragm. To date, no pediatric study has focused on the effects of NAVA on hemodynamic parameters. This physiologic study with a randomized cross-over design compared hemodynamic parameters when NAVA or conventional ventilation (CV) was applied.

Methods

After a baseline period, infants received NAVA and CV in a randomized order during two consecutive 30-min periods. During the last 10 min of each period, respiratory and hemodynamic parameters were collected. No changes in PEEP, FiO₂, sedation or inotropic doses were allowed during these two periods. The challenge was to keep minute

SUBMITTER: Liet JM 

PROVIDER: S-EPMC5100099 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature