Metabolic profiling of alcohol consumption in 9778 young adults.

ABSTRACT:

Background

High alcohol consumption is a major cause of morbidity, yet alcohol is associated with both favourable and adverse effects on cardiometabolic risk markers. We aimed to characterize the associations of usual alcohol consumption with a comprehensive systemic metabolite profile in young adults.

Methods

Cross-sectional associations of alcohol intake with 86 metabolic measures were assessed for 9778 individuals from three population-based cohorts from Finland (age 24-45 years, 52% women). Metabolic changes associated with change in alcohol intake during 6-year follow-up were further examined for 1466 individuals. Alcohol intake was assessed by questionnaires. Circulating lipids, fatty acids and metabolites were quantified by high-throughput nuclear magnetic resonance m

SUBMITTER: Wurtz P 

PROVIDER: S-EPMC5100616 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature