Quality of life at 6 months in the Idiopathic Intracranial Hypertension Treatment Trial.

ABSTRACT:

Objective

To examine the changes in vision-specific and overall health-related quality of life (QOL) at 6 months in participants with idiopathic intracranial hypertension (IIH) and mild visual loss enrolled in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) and to determine the signs and symptoms of IIH that mediate the effect of acetazolamide on QOL.

Methods

We assessed QOL using the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25), the 10-Item NEI-VFQ-25 Neuro-Ophthalmic Supplement, and the 36-Item Short Form Health Survey (SF-36). We examined associations among changes in QOL measures over 6 months, treatment status, and changes in signs and symptoms using linear and structural equation models.

Results

Among the 165 participants

SUBMITTER: Bruce BB 

PROVIDER: S-EPMC5100710 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature