Treatment of trauma-affected refugees with venlafaxine versus sertraline combined with psychotherapy - a randomised study.

ABSTRACT:

Background

The prevalence of trauma-related psychiatric disorders is high among refugees. Despite this, little is known about the effect of pharmacological treatment for this patient group. The objective of the present study was therefore to examine differences in the effects of venlafaxine and sertraline on Post-Traumatic Stress Disorder (PTSD), depression and functional impairment in trauma-affected refugees.

Methods

The study was a randomised pragmatic trial comparing venlafaxine and sertraline in combination with psychotherapy and social counselling. PTSD symptoms were measured on the Harvard Trauma Questionnaire - part IV, which was the primary outcome measure. Other outcome measures included: Hopkins Symptom Check List-25 (depression and anxiety), Social Adjustment Sca

SUBMITTER: Sonne C 

PROVIDER: S-EPMC5101827 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature