Association Between Rotating Night Shift Work and Risk of Coronary Heart Disease Among Women.

ABSTRACT:

Importance

Prospective studies linking shift work to coronary heart disease (CHD) have been inconsistent and limited by short follow-up.

Objective

To determine whether rotating night shift work is associated with CHD risk.

Design, setting, and participants

Prospective cohort study of 189,158 initially healthy women followed up over 24 years in the Nurses' Health Studies (NHS [1988-2012]: N = 73,623 and NHS2 [1989-2013]: N = 115,535).

Exposures

Lifetime history of rotating night shift work (≥3 night shifts per month in addition to day and evening shifts) at baseline (updated every 2 to 4 years in the NHS2).

Main outcomes and measures

Incident CHD; ie, nonfatal myocardial infarction, CHD death, angiogram-confirmed angina pectoris, coronary artery bypass gr

SUBMITTER: Vetter C 

PROVIDER: S-EPMC5102147 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature