A study of the electro-haemodynamic coupling using simultaneously acquired intracranial EEG and fMRI data in humans.

ABSTRACT: In current fMRI studies designed to map BOLD changes related to interictal epileptiform discharges (IED), which are recorded on simultaneous EEG, the information contained in the morphology and field extent of the EEG events is exclusively used for their classification. Usually, a BOLD predictor based on IED onset times alone is constructed, effectively treating all events as identical. We used intracranial EEG (icEEG)-fMRI data simultaneously recorded in humans to investigate the effect of including any of the features: amplitude, width (duration), slope of the rising phase, energy (area under the curve), or spatial field extent (number of contacts over which the sharp wave was observed) of the fast wave of the IED (the sharp wave), into the BOLD model, to better understand the neurophysi

SUBMITTER: Murta T 

PROVIDER: S-EPMC5102699 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature