Obstructive sleep apnea and incident type 2 diabetes.

ABSTRACT:

Objectives

To determine whether severity of obstructive sleep apnea is associated with incident diabetes in middle-aged and older adults.

Methods

A prospective analysis of 1453 non-diabetic participants of both the Atherosclerosis Risk in Communities Study and the Sleep Heart Health Study (mean age 63 years, 46% male) had in-home polysomnography (1996-1998) and was followed up for incident diabetes. Using the apnea-hypopnea index derived from home polysomnography, study participants were categorized as follows: <5.0 (normal), 5.0-14.9 (mild), 15.0-29.9 (moderate), and ≥30.0 events/h (severe). Incident diabetes was ascertained during annual follow-up telephone calls through 2013.

Results

During a median follow-up of 13 years, there were 285 incident diabetes cases amon

SUBMITTER: Nagayoshi M 

PROVIDER: S-EPMC5102826 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature