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Development of putative probiotics as feed additives: validation in a porcine-specific gastrointestinal tract model.


ABSTRACT: Enforced restrictions on the use of antibiotics as growth promoters (AGPs) in animal production have prompted investigations into alternative feed additives in recent decades. Probiotics are currently the main feed additive used in livestock. However, the selection of probiotic candidates relies on human-based methods and little is known about the verification criteria for host-specific selection. We investigated the probiotic potential of Lactobacillus salivarius strains isolated from fed pig feces for their use as porcine feed additives. Two methods were developed that simulated the pig gastrointestinal (GI) tract and the intestinal epithelium, and these were compared with human-based in vitro methods and used for selecting porcine probiotics. Lactobacillus salivarius strain LS6 was iden

SUBMITTER: Yeo S 

PROVIDER: S-EPMC5102953 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature