Computational identification of genes modulating stem height-diameter allometry.
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ABSTRACT: The developmental variation in stem height with respect to stem diameter is related to a broad range of ecological and evolutionary phenomena in trees, but the underlying genetic basis of this variation remains elusive. We implement a dynamic statistical model, functional mapping, to formulate a general procedure for the computational identification of quantitative trait loci (QTLs) that control stem height-diameter allometry during development. Functional mapping integrates the biological principles underlying trait formation and development into the association analysis of DNA genotype and endpoint phenotype, thus providing an incentive for understanding the mechanistic interplay between genes and development. Built on the basic tenet of functional mapping, we explore two core ecological
SUBMITTER: Jiang L
PROVIDER: S-EPMC5103235 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
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