Acute Sleep Deprivation Blocks Short- and Long-Term Operant Memory in Aplysia.

ABSTRACT:

Study objectives

Insufficient sleep in individuals appears increasingly common due to the demands of modern work schedules and technology use. Consequently, there is a growing need to understand the interactions between sleep deprivation and memory. The current study determined the effects of acute sleep deprivation on short and long-term associative memory using the marine mollusk Aplysia californica, a relatively simple model system well known for studies of learning and memory.

Methods

Aplysia were sleep deprived for 9 hours using context changes and tactile stimulation either prior to or after training for the operant learning paradigm, learning that food is inedible (LFI). The effects of sleep deprivation on short-term (STM) and long-term memory (LTM) were

SUBMITTER: Krishnan HC 

PROVIDER: S-EPMC5103805 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature