Asthma phenotypes in inner-city children.

ABSTRACT:

Background

Children with asthma in low-income urban areas have high morbidity. Phenotypic analysis in these children is lacking, but may identify characteristics to inform successful tailored management approaches.

Objective

We sought to identify distinct asthma phenotypes among inner-city children receiving guidelines-based management.

Methods

Nine inner-city asthma consortium centers enrolled 717 children aged 6 to 17 years. Data were collected at baseline and prospectively every 2 months for 1 year. Participants' asthma and rhinitis were optimally managed by study physicians on the basis of guidelines. Cluster analysis using 50 baseline and 12 longitudinal variables was performed in 616 participants completing 4 or more follow-up visits.

Results

Five cluster

SUBMITTER: Zoratti EM 

PROVIDER: S-EPMC5104222 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature