Neurofunctional Abnormalities during Sustained Attention in Severe Childhood Abuse.

ABSTRACT: Childhood maltreatment is associated with adverse affective and cognitive consequences including impaired emotion processing, inhibition and attention. However, the majority of functional magnetic resonance imaging (fMRI) studies in childhood maltreatment have examined emotion processing, while very few studies have tested the neurofunctional substrates of cognitive functions and none of attention. This study investigated the association between severe childhood abuse and fMRI brain activation during a parametric sustained attention task with a progressively increasing load of sustained attention in 21 medication-naïve, drug-free young people with a history of childhood abuse controlling for psychiatric comorbidities by including 19 psychiatric controls matched for psychiatric diagnoses, a

SUBMITTER: Lim L 

PROVIDER: S-EPMC5104469 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature