Heart rate variability during sleep in children with autism spectrum disorder.

ABSTRACT:

Purpose

Autonomic dysfunction has been reported in autism spectrum disorders (ASD). Less is known about autonomic function during sleep in ASD. The objective of this study is to provide insight into the autonomic cardiovascular control during different sleep stages in ASD. We hypothesized that patients with ASD have lower vagal and higher sympathetic modulation with elevated heart rate, as compared to typical developing children (TD).

Methods

We studied 21 children with ASD and 23 TD children during overnight polysomnography. Heart rate and spectral parameters were calculated for each vigilance stage during sleep. Data from the first four sleep cycles were used to avoid possible effects of different individual sleep lengths and sleep cycle structures. Linear regression model

SUBMITTER: Harder R 

PROVIDER: S-EPMC5106315 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature