Trajectories of Lower Extremity Physical Performance: Effects on Fractures and Mortality in Older Women.

ABSTRACT:

Background

Prior studies have only considered one measurement of physical performance in its relationship to fractures and mortality. A single measurement is susceptible to large within-person changes over time, and thus, may not capture the true association between physical performance and the outcomes of interest.

Methods

Using data from the Study of Osteoporotic Fractures, we followed 7,015 women enrolled prior to age 80 years who had outcome information beyond this age. Trajectories of walking speed (m/s) and chair stand speed (stands/s) were estimated up to the last visit prior to age 80 years using mixed-effects linear regression. Physical performance at age 80 (PF_age80) was assessed at the last visit prior to age 80 years. Hazard ratios (HRs) and 95% confidence inter

SUBMITTER: Barbour KE 

PROVIDER: S-EPMC5106858 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature