Factor analysis of temperament and personality traits in bipolar patients: Correlates with comorbidity and disorder severity.

ABSTRACT:

Background

Temperament and personality traits have been suggested as endophenotypes for bipolar disorder based on several lines of evidence, including heritability. Previous work suggested an anxious-reactive factor identified across temperament and personality inventories that produced significant group discrimination and could potentially be useful in genetic analyses. We have attempted to further characterize this factor structure in a sample of bipolar patients.

Methods

A sample of 1195 subjects with bipolar I disorder was evaluated, all with complete data available. Dimension reduction across two inventories identified 18 factors explaining 39% of the variance.

Results

The two largest factors reflected affective instability and general anxiety/worry, respectively

SUBMITTER: Qiu F 

PROVIDER: S-EPMC5107122 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature