Rhodomollins A and B, two Diterpenoids with an Unprecedented Backbone from the Fruits of Rhododendron molle.

ABSTRACT: Two new grayanoids, rhodomollin A (1) and rhodomollin B (2), possessing an unprecedented D-homo grayanane carbon skeleton, were isolated from the fruits of Rhododendron molle. The structures of 1 and 2 were fully characterized using a combination of spectroscopic analyses and X-ray crystallography. Rhodomollin B (2) exhibited modest activity against influenza virus A/95-359, with an IC₅₀ value of 19.24 μM.

SUBMITTER: Li Y 

PROVIDER: S-EPMC5107939 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature