Left ventricular ejection fraction recovery in patients with heart failure treated with intravenous iron: a pilot study.

ABSTRACT:

Aims

In patients with heart failure with reduced ejection fraction (HFrEF) and iron deficiency, treatment with intravenous iron has shown a clinical improvement regardless of anaemic status. Cardiac magnetic resonance (CMR) T2* sequence has shown a potential utility for evaluating myocardial iron deficiency. We aimed to evaluate whether T2* sequence significantly changes after ferric carboximaltose (FCM) administration, and if such changes correlate with changes in left ventricle ejection fraction (LVEF).

Methods and results

In this pilot study, we included eight patients with chronic symptomatic (New York Heart Association II-III) HFrEF and iron deficiency. A CMR, including T2* analysis, was performed before and at a median of 43 days (interquartile range = 35-48) after int

SUBMITTER: Nunez J 

PROVIDER: S-EPMC5107972 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature