Importance of sperm morphology during sperm transport and fertilization in mammals.

ABSTRACT: After natural or artificial insemination, the spermatozoon starts a journey from the site of deposition to the place of fertilization. However, only a small subset of the spermatozoa deposited achieves their goal: to reach and fertilize the egg. Factors involved in controlling sperm transport and fertilization include the female reproductive tract environment, cell-cell interactions, gene expression, and phenotypic sperm traits. Some of the significant determinants of fertilization are known (i.e., motility or DNA status), but many sperm traits are still indecipherable. One example is the influence of sperm dimensions and shape upon transport within the female genital tract towards the oocyte. Biophysical associations between sperm size and motility may influence the progression of spermat

SUBMITTER: Garcia-Vazquez FA 

PROVIDER: S-EPMC5109874 | biostudies-literature | 2016 Nov-Dec

REPOSITORIES: biostudies-literature