Subtle in-scanner motion biases automated measurement of brain anatomy from in vivo MRI.

ABSTRACT: While the potential for small amounts of motion in functional magnetic resonance imaging (fMRI) scans to bias the results of functional neuroimaging studies is well appreciated, the impact of in-scanner motion on morphological analysis of structural MRI is relatively under-studied. Even among "good quality" structural scans, there may be systematic effects of motion on measures of brain morphometry. In the present study, the subjects' tendency to move during fMRI scans, acquired in the same scanning sessions as their structural scans, yielded a reliable, continuous estimate of in-scanner motion. Using this approach within a sample of 127 children, adolescents, and young adults, significant relationships were found between this measure and estimates of cortical gray matter volume and mean c

SUBMITTER: Alexander-Bloch A 

PROVIDER: S-EPMC5110234 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature