Over or under: hydride attack at the metal versus the coordinated nitrosyl ligand in ferric nitrosyl porphyrins.

ABSTRACT: Hydride attack at a ferric heme-NO to give an Fe-HNO intermediate is a key step in the global N-cycle. We demonstrate differential reactivity when six- and five-coordinate ferric heme-NO models react with hydride. Although Fe-HNO formation is thermodynamically favored from this reaction, Fe-H formation is kinetically favored for the 5C case.

SUBMITTER: Abucayon EG 

PROVIDER: S-EPMC5110368 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature