Project description:The goal of this project was to use differential kinobeads profiling for the discrimination of reversible and irreversible kinase targets of different covalent kinase inhibitors. For this, differences in target engagement measured in a lysate- and a cell-based kinobeads assay were compared in a kinome-wide scale.

2017-10-13 | PXD007920 | Pride

Profiling charge complementarity and selectivity for binding at the protein surface.

Project description: Not available

| S-EPMC1302852 | biostudies-literature