Standard corneal collagen crosslinking versus transepithelial iontophoresis-assisted corneal crosslinking, 24 months follow-up: randomized control trial.

ABSTRACT:

Purpose

To compare the results of standard corneal crosslinking (CXL) and transepithelial iontophoresis-assisted CXL after 24 months follow-up.

Material and methods

Corneal crosslinking (CXL) was performed in a series of 149 eyes of 119 patients with keratoconus I-II of Amsler classification. Depending on the CXL method, patients were divided into two groups: (1) 73 eyes with standard CXL and (2) 76 eyes with transepithelial iontophoresis-assisted CXL. Depending on the group, epithelium removal or administration of riboflavin solution by iontophoresis for 10 min was performed, after which standard surface UVA irradiation (370 nm, 3 mW/cm² ) was performed at a 5-cm distance for 30 min.

Results

A statistically significant difference in corrected distance visu

SUBMITTER: Bikbova G 

PROVIDER: S-EPMC5111766 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature